High Throughput Screening
Automated liquid handling, plate-based assay development, and label-free mass spectrometry for rapid compound screening and hit identification
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The Echo® MS+ system combines acoustic droplet ejection (ADE) with triple quadrupole and high-resolution accurate mass (HRAM) detection, enabling contactless, ultra-fast sample introduction that eliminates bottlenecks and minimizes cross-contamination. This technology is ideal for workflows demanding high sample integrity, reproducibility, and throughput.
Designed for Consistent Performance
A built-in port wash system automatically cleans between sample plates, increasing ejection capacity and ensuring high-quality data without frequent manual intervention.
Intelligent Software Integration
Powered by SCIEX OS software, which automates both data acquisition and processing – optimized for both small and large molecule analysis.
Proven Compatibility
Integrates seamlessly with the SCIEX Triple Quad 6500+ or ZenoTOF 7600 systems, delivering reliable, high-resolution data for confident decision-making.
Automation and Liquid Handling
384/96 Well Plate Transfer
Cybio Vario with 384 and 96 well heads and Eppendorf EP96 enable rapid, precise plate-to-plate compound transfer for large-scale screening campaigns.
Customizable and Multi-Format Liquid Handling
* Mantis Microfluidic Liquid Dispensar
* Eppendorf EP Motion
* Integra Assist & Assist Plus
* Integra Welljet
* Cybio 8plus1
Small Molecule Libraries: ~120,000 small molecules with high structural diversity to cover a broad chemical space.
Plate Readers and Assay Development
Plate Reading Capabilities
* Absorbance
* Fluorescence
* Luminescence
* Fluorescence Polarization
* Alpha-Screening
Available Plate Readers
* BMG Omega (×2)
* BMG Clariostar
* Thermo Multiscan GO
* Thermo Varioskan LUX
Other Assay Development Equipment
* NT Monolith – Binding Kinetics
* NT Prometheus – Thermal Shift
* Agilent qRT PCR
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The Echo 650 supports transfers from 384- and 1536-well microplates and is well suited for compound screening, assay development, dose-response studies, and other low-volume, high-throughput workflows.